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The production of endorphins in tissues in response to nerve stimulation relieves inflammation and pain. Dr. Oz and the medical community seem to forget that hot and cold receptors in the skin can be readily triggered by natural products in foods, to stimulate the release of endorphins and treat inflammation in nearby tissues. Hot and Cold Dont Easily Penetrate the Skin Athletic trainers commonly apply hot and cold packs to avoid swelling and inflammation from injuries, and they are always discussing the virtues of various hot/cold regimens. They ignore the extraordinary efficiency of the circulatory system in regulating tissue temperatures and avoiding temperature changes. They also ignore the fact that chemical "hot and cold" salves and ointments are effective without actually changing the temperature of the skin. The essential observation is that triggering hot and cold sensing nerves is more important than changing the temperature of the damaged tissues. Common Food M...

Glucosamine supplements work through effects on the gut that contribute to general anti-inflammation. It is thought that glucosamine interacts with tissue transglutaminase and blocks production of signaling molecules for chronic infammation. It should also be effective against inflammatory diseases of the intestines, joints and elsewhere. Cartilage and other connective tissues are made up of collagen protein fibers embedded in a matrix of polysaccharide, chondroitin sulfate. The tightly packed, twisted proteins of the collagen in the negatively charged, acidic polysaccharide act like a fiber reinforced, dense gel that provides impact resistance for long bone joint surfaces, as well as the stretch-resistance and elasticity for tendon and ligaments. Collagen in cartilage is comparable to cellulose (crystallin neutral polysaccharide fibers) embedded in the acidic polysaccharide (pectin) of plant cell walls. The connective tissue polysaccharides are glycosamino glycans, GAGs, the most...