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Vitamin B12 and Disease

Vitamin B12 and the associated amino acids methionine and cysteine are essential to avoid specific symptoms of anemia and the deleterious effects of inflammation. Vitamin B12, cobalamin, cannot be made by the human body and requires a protein secreted by stomach cells, intrinsic protein, for uptake from the diet or from gut bacteria. In the absence of dietary B12, individuals can develop pernicious anemia. Since vitamin B12 is used by enzymes involved in nucleic acid synthesis, the rapidly dividing cell of the blood show the first symptoms. Another feature of pernicious anemia is the production of autoimmune antibodies against gastric intrinsic protein. This means that even if the diet is supplemented with vitamin B12, the anemic patient would show no improvement. Historically, the cure was beef liver juice containing B12 already bound to intrinsic factor. I enjoyed learning about the autoimmune aspect of pernicious anemia, because when I examined the sequence of the human i...

News Quickie Vitamin D Could Increase IGF 1 Delivery to the Muscle Plus Ergogenic Juicing For Ultra Marathoners

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Marathon de Sable ➯ Tomato juice Its about time for another quickie, a news quickie about exercise & supplementation, about vitamin D and tomato juice... actually its rather about tomato juice, a special carbohydrate + protein bar and the notorious "Gatorate(R)-ish" carbohydrate supplement every endurance athlete believes he must be taking. But lets be honest, who cares about tomato juice, carbohydrate, protein bars, pseudo Gatorade and their individual and joint effects on the health and performance of constantly (over-)taxed ultra-marathoners, if the other new item in todays article deals with the potential beneficial effect of vitamin D on IGF-1 and its anabolic consequences? You can learn more about protein, tomatoes and vitamin D at the SuppVersity Are You Protein Wheysting? Vitamin D Speeds up Recovery Protein requ. of athletes Vitamin D, Muscle & Myostatin Tomaotorade(R) Intra-Workout Too much ado about protein? You care? Ok, in that case, you may be inclined ...